Improvement of Dystonia after Spinal Cord Injury by Applying Repetitive Transcranial Magnetic Stimulation on the Premotor Cortex: Case Report

GU Chun-ya, CHENG Yuan ZHAO Li-juan, XU Dong-sheng

Abstract

This article reports a patient with spinal cord injury who was treated with conventional rehabilitation therapy plus repeated transcranial magnetic stimulation (rTMS) during the postoperative rehabilitation, and to observe the effects of rTMS on dystonia. A 66-year-old male patient fell from the bed 8 months ago. At that time, he felt pain in his neck, dysfunction in limbs movement, and loss of sensation in trunk and limbs. Magnetic resonance imaging (MRI) revealed spinal cord injury. Under general anesthesia, anterior cervical decompression and bone graft fusion (ACDF) and cervical spine internal fixation of C3-C6 were performed. Postoperative hyperbaric oxygen chamber and conventional rehabilitation treatment were performed. Eight months after surgery, he was admitted to the hospital due to motor function, balance dysfunction, neurogenic bladder/rectal dysfunction. After admission, the patient was treated with rTMS plus rehabilitation treatment, once per day, 5 times/week, for 4 weeks. rTMS worked by wearing a positioning cap for transcranial magnetic stimulation (80% resting motor threshold, 1 Hz, 30 min), and then conduct walking, balance proprioception, muscle strength training, and coordination training. After 4 weeks, MEP, sEMG and H reflex were improved. Therefore, rTMS on the premotor cortex to improve the dystonia after spinal cord injury is effective in this case, which can be further studied.

 

Keywords: rTMS, Spinal cord injury, Dystonia

 

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References


CRIPPS R A， LEE B B， WING P， et al. A global map for traumatic spinal cord injury epidemiology: towards a living data repository for injury prevention. Spinal Cord，2011，4(4): 493–501.

ROTENBERG A， HORVATH J C， PASCUAL-LEONE A. Transcranial magnetic stimulation. Humana Press: New York， 2014: 133.

PIZZI A， CARLUCCI G， FALSINI C， et al. Evaluation of upper-limb spasticity after stroke: a clinical and neurophysiologic study. Arch Phys Med Rehabil，2005，86(3): 410–415.

LEFAUCHEUR J P， ANDRE-OBADTA N， ANTAL A， et al. Evidence-based guideline on the therapeutic of repetitive transcranial magnetic stimulation. Clin Neurophysiol，2014，125(11): 2150–2206.

ZAAIMI B， DEAN L R， BAKER S N. Different contributions of primary motor cortex, reticular formation, and spinal cord to fractionated muscle activation. J Neurophysiol，2018，119(1): 235–250.

RADMAN T， RAMOS R L， BRUMBERG J C， et al. Role of cortical cell type and morphology in sub-and suprathreshold uniform electric field stimulation. Brain Stimul，2009，2(4): 215–228.

DU X M， CHOA F S， SUMMERFELT A， et al. Neural summation in human motor cortex by subthreshold transcranial magnetic stimulations. Exp Brain Res，2015，233(2): 671–677.

LOZERON P， POUJOIS A， RICHARD A， et al. Contribution of TMS and rTMS in the understanding of the pathophysiology and in the treatment of dystonia. Front Neural Circuits，2016，10(90): 6–7.

THOMPSON A K， WOLPAW J R. Restoring walking after SCI: operant conditioning of spinal reflexes can help. Neuroscientist，2015，21(2): 204–208.


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