Dietary Factors Associated with Hyperuricemia and Glyeolipid Metabolism Disorder in Middle-aged and Elderly People

ZHU Jia-ni, QI Xin-yue, TAN Yang. et al

Abstract

To identify dietary factors associated with glyeolipid metabolism disorder and hyperuricemia in middle-aged and elderly people. Methods 183 visitors to a community health service center for physical examinations and 241 respiratory patients admitted to a hospital ward were randomly selected. The prevalence of hyperuricemia and dyslipidemic diabetics in the two groups of participants was investigated. Dietary information was collected using a semi-quantitative food frequency questionnaire. Results ① Male participants had a higher level of prevalence of hyperuricemia than female (P<0.01). ②Hypoglycemia, hypercholesterolemia, hypertriglyceridemia and excessive intake of meat, poultry, alcohol, energy and fat were risk factors of hyperuricemia (P<0.05); whereas, moderate intake of vegetables and fruits were protective factors (P<0.01). Conclusion Hyperuricemia is associated with glyeolipid metabolism disorder and dietary factors. Early monitoring of glucose and lipid metabolism and dietary interventions in high risk population may play an important role in the prevention of hyperuricemia.

 

Keywords: Middle-aged and elderly people, Hyperuricemia, Glyeolipid metabolism disorder, Dietary, Nutrient 

 

Full Text:

PDF


References


Karis Е, Crittenden DB, Pillinger МН. Hyperuricemia, gout, and related comorbidities: cause and effect on a two-way street. South Med J ,2014 ; 107(4) :235-241.

Expent Panel on Detection, Evalution, and Treatment of High Blood Cholesterol in Adults. Executive summary of the Third report of the national cholesterol education program (NCEP) Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults ( Adult Treatment Panel III ). JAMA,2001 ;285( 19):2486-2497.

Chen JH, Yeh WT, Chuang SY, et al. Gender-specific risk factors for incident gout; a prospective cohort study. Clin Rheumatol. 2012; 31 (2): 239-245.

Ye X.Cao Y.Gao F,e*/ al. Elevated serum uric acid levels are independent risk factors for diabetic foot ulcer in female Chinese patients with type 2 diabetes. J Diabetes,2014 ;6( 1):42-47.

Yuan HJ,Yang XG.Shi XY ■> et al. Association of serum uric acid with different levels of glucose and related fators. Chin Med J (Engl),2011; 124 (10); 1443-1448.

Karalis DG. Intensive lowering of low-density lipoprotein cholesterol levels for primary prevention of coronary artery disease. Mayo Clin Proc,2009;84(4);345-352.

Assmann G, Cullen P, Erbey J, et at. Plasma sitosterol elevations are associated with an increased incidence of coronary events in men; results of a nested case-control analysis of the prospective cardiovascular mtinster( PR ( X; AM) study. Nutr Metab cardiovasc Dis,2006 ; 16(1): 13-21.

Enquobahrie DA, Williams МЛ, Qiu С, etal. Early pregnancy lipid concentrations and the risk of gestational diabetes mellitus. Diabetes Res Clin Pract,2005;70(2): 134-142.

Li G. Kong L, Zhang L, et al. Early pregnancy maternal lipid profiles and the risk of gestational diabetes mellitus stratified for body mass index. Reproduct Sci.2015;22(6):712-717.

Facchinetti F, Dante G, Petrella E, et al. Dietary interventions, lifestyle changes, and dietary supplements in preventing gestational diabetes mellitus; a literature review. Obstet Gynecol Survey,2014 ; 69(11); 669-680.

Oken E. Ning Y, Rifas-Shiman SL, et al. Associations of physical activity and inactivity before and during pregnancy with glucose tolerance. Obstet Gynecol.2006? 108(5); 1200.

Bellamy L. Casas JP. Hingorani AD. et al. Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet.2009;373(9677); 1773-1779.

Savvidou M. Nelson SM. Makgoba M. et al. First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures. Diabetes,2010;59(12):3017-3022.

Vrijkotte TG. Krukziener N, Hutten BA, et al. Maternal lipid profile during early pregnancy and pregnancy complications and outcomes: the ABCD study. J Clin Endocrinol Metabol, 2012; 97(ll):3917-3925.

De Graaf J. Hak-Lemmers HL. Hectors MP, et al. Enhanced susceptibility to in vitro oxidation of the dense low density lipoprotein sub-fraction in healthy subjects. Arterioscl Throm Vas,1991;11(2):298-306.

Hurt-Camejo E, Camejo G, Rosengren B. et al. Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells. Arterioscl Throm Vas, 1992;12 (5);569-583.

Kajimoto Y. Kaneto H. Role of oxidative stress in pancreatic (3-cell dysfunction. Ann New York Acad Sci, 2004; 1011 ( 1 ); 168-176.

Kelley DE, Goodpaster BH. Skel,et al muscle triglyceride. An aspect of regional adiposity and insulin resistance. Diabetes Care,2001;24(5):933-941.


Refbacks

  • There are currently no refbacks.